T R A C K       P A P E R

Login Panel

Close tab

Password Meter

Volume 17 Issue 1

S.No. Title & Authors Page No View
1

Title : Cutaneous Toxicity of Anti-EGFR in NSCLC in the National Oncology Institute of Rabat: A Literature Review and a Clinical Case

Authors : Nadir Wydad , Hachlaf Mariem , Abdi Chaimae , Lkhoyaali Siham , Mrabti Hind, El Ghissassi Brahim , Boutayeb Saber , Errihani Hassan

Click Here For Abstract

Download Certificate
Abstract :

The inhibitors of the epidermal growth factor receptor (EGFR) have revolutionized the treatment of various cancers, notably non-small cell lung cancer (NSCLC). However, their clinical utility is often hindered by their cutaneous toxicity. Within this review, we report an illustrative clinical case of a 59-year-old patient with metastatic non-small cell lung cancer treated with erlotinib. After three months of treatment, she developed grade III cutaneous toxicity, presenting as an extensive squamous-papular rash on the limbs. Management of this toxicity involved suspending erlotinib treatment for two weeks, accompanied by curative doxycycline therapy. This clinical case is discussed in light of the literature, highlighting the clinical aspects, prevalence, and management of cutaneous adverse effects associated with anti-EGFR agents.Proactive and preventive management of these side effects is essential to maximize the clinical benefits of these agents while improving patients quality of life.

01-04